miRNAs: Optional for Cancer?

A review on miRNAs as new biomarkers for colorectal cancer

Background & Objective: Since colorectal cancer does not often have phenotypic symptoms in the early stages, the study of biomarkers for the diagnosis and prognosis of the tumor is very important. MicroRNAs are one of the most important biomarkers which attract the attention of many researchers due to a variety of reasons, including their non-invasive nature; these molecules are a group of non-...

Diagnostic Utility of miRNAs in Cancer

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

Diagnostic Utility of miRNAs in Cancer

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

miRNAs and cancer

MicroRNAs (miRNAs) are small 21-25 nucleotide RNA molecules that comprise an evolutionarily conserved class of ribo-regulators which modulate gene expression via the RNA interference pathway. Initially considered a peculiarity of nematodes it is now known that these small non protein coding RNAs also occur in a wide variety of other organisms like plants, arthropods and vertebrates such as amph...

miRNAs in Pancreatic Cancer